Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 10:08 PM
Ignite Modification Date:
2025-12-24 @ 10:08 PM
NCT ID:
NCT06958835
Eligibility Criteria:
Inclusion criteria:
* Staphylococcus aureus (S. aureus) grown from at least one blood culture
* Hospitalised at a participating centre
* ≥18 years old
* Written informed consent or fulfilling criteria for an emergency exception from informed consent requirements
Exclusion criteria:
* Administration of the initial drug treatment not feasible within 72 hours since the collection of the first positive blood culture with S. aureus
* Documented history of positive blood cultures for S. aureus occurring between 72 hours and 180 days prior to the eligibility assessment
* Necrotising fasciitis
* Currently receiving linezolid or clindamycin
* Use of any monoamine oxidase A or B inhibitor within the last two weeks
* Known hypersensitivity to linezolid or any other ingredients of the study drugs
* Current severe thrombocytopenia (i.e. \<30 x 10\^9/L)
* Application of study drug not possible (per mouth or per gastric tube)
* Currently breastfeeding
* Local treating team believes that death is imminent and inevitable
* Patient is receiving end of life care and antibiotic treatment is not considered appropriate
* Local treating team believes that participation in the study is not in the best interest of the patient
* Any indication that the patient is unwilling to participate in the study including an advance directive stating such unwillingness
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT06958835
Study Brief:
Protocol Section:
NCT06958835