Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 10:07 PM
Ignite Modification Date:
2025-12-24 @ 10:07 PM
NCT ID:
NCT01134835
Eligibility Criteria:
Inclusion Criteria:
* Age 18-75 of either sex with a clinical diagnosis of asthma,
* FEV1 ≥ 60% predicted and an increase in FEV1 of greater than 12% following inhaled salbutamol 400μg or Peak Expiratory Flow (PEF) variability \>12% during run-in.
* Allowed medication: 0-800μg inhaled beclomethasone diproprionate or equivalent and as required short acting beta agonist.
Exclusion Criteria:
* Current smoking,
* \> 10 pack years smoking history,
* Treatment with leukotriene antagonists,
* Liver or cardiovascular disease,
* Oral steroid treatment or exacerbation within 6 weeks,
* Females who are pregnant, lactating or not using adequate contraception,
* Any contra-indication to pioglitazone (hypersensitivity to pioglitazone, cardiac failure, history of cardiac failure, hepatic impairment, diabetic ketoacidosis),
* Oral or insulin treatment for diabetes,
* Treatment with gemfibrozil or rifampicin.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
75 Years
Study:
NCT01134835
Study Brief:
Protocol Section:
NCT01134835