Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 10:03 PM
Ignite Modification Date:
2025-12-24 @ 10:03 PM
NCT ID:
NCT00825435
Eligibility Criteria:
Inclusion Criteria:
* patients who complain of typical or atypical chest pain (that is compatible with ischemia during the past 12 hrs);
* patients a prediction of low to intermediate risk of myocardial infarction and/or complications according to established criteria;
* patients who have normal or non-diagnostic electrocardiograms;
* patients who have negative cardiac biomarker including creatine kinase-MB, myoglobin, and/or cardiac troponin I at initial testing; patients who require admission to the hospital by the EP at the time of risk-stratification;
* patients who require cardiology consultation in the ED 7. patients who are age 35 years or older;
* patients who are able to hold their breath for ≥ 15 seconds (to obtain a quality static anatomical image, scanning requires at least fifteen seconds of breath holding;
* patients who have heart rate of \< 70 beats per minute before or after the administration of beta-blocker medication
Exclusion Criteria:
* patients who have a contraindication to iodinated and/ or beta-blocking drugs; patients who have compromised renal function defined as creatinine ≥ 1.2 mg/dl;
* patients who are pregnant, suspected pregnant or other vulnerable populations e.g., incarcerated patients;
* patients who have documented CAD by prior invasive coronary angiography or coronary CT angiography and/or patients with coronary artery stents, prior angioplasty, or prior coronary artery bypass grafts (CABG);
* patients who have had prior cardiac imaging (within the past year) with normal result including invasive coronary angiography, coronary CT angiography, or nuclear stress testing;
* patients who are unstable; patients who have an electrocardiogram diagnostic of ischemia or myocardial infarction (significant Q waves, ST -segment deviations \> 0.5 mm, or T wave inversions);
* patients in atrial fibrillation or have markedly irregular rhythm 9. patients who have had contrast administration within the past 24hrs;
* patients without an 18 gauge antecubital intravenous access; patients who have a medical home outside of the UTSWMC/Parkland Medical system.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
35 Years
Study:
NCT00825435
Study Brief:
Protocol Section:
NCT00825435