Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 10:02 PM
Ignite Modification Date:
2025-12-24 @ 10:02 PM
NCT ID:
NCT01368432
Eligibility Criteria:
Inclusion Criteria:
* Closed head injury
* Fulfill Diagnostic and Statistical Manual Diploma in Social Medicine (DSM) IV criteria "Major Depressive Disorder"
* 18 years of age or older
* Able to provide informed consent
* Stable medical history
Exclusion Criteria:
* History of Stroke, Encephalitis, Seizures, or any other pre-TBI neurological diseases
* History of mental retardation
* Alcohol or Substance dependence in the last 1 year
* Inability to undergo MRI scan
* Pregnancy
* Current use of any psychotropic medications including any antidepressants, antipsychotics, anxiolytics, or sedative hypnotics
* Poor response to escitalopram in the past
* Acutely suicidal or requiring inpatient psychiatric hospitalization, as determined by the study psychiatrist
* Good medication response to another antidepressant in the past
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT01368432
Study Brief:
Protocol Section:
NCT01368432