Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 10:01 PM
Ignite Modification Date:
2025-12-24 @ 10:01 PM
NCT ID:
NCT03306732
Eligibility Criteria:
Inclusion Criteria:
* Valve surgery + CABG that required cardiac surgery with CPB
* Aged 18 years or older
* Signed informed consent
Exclusion Criteria:
* Emergency surgery
* Chronic kidney disease of G4-G5 categories according to KDIGO criteria (at least one of the following present for \> 3 months: glomerular filtration rate ≤ 29 ml/min/1.73 m2, history of kidney transplantation)
* Known allergy to thiamine
* Pregnancy
* Current enrollment into another RCT (in the last 30 days)
* Previous enrollment and randomisation into the APPLY trial
* Administration of thiamine in the previous 30 day
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT03306732
Study Brief:
Protocol Section:
NCT03306732