Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 9:56 PM
Ignite Modification Date:
2025-12-24 @ 9:56 PM
NCT ID:
NCT05997732
Eligibility Criteria:
Inclusion Criteria:
* Between ages 18-40 years
* No diagnosed medical history of cardiovascular, respiratory, nervous system, or metabolic disease.
* Females must be pre-menopausal.
* Prior to study visit: abstained from caffeine, alcohol, strenuous exercise, and medication not taken regularly for at least 12 hours.
Exclusion Criteria:
* Current diagnosis of cardiovascular, respiratory, nervous system, or metabolic disease that may impact blood pressure regulation. This will be assessed on a case-by-case basis by the study physician.
* Participants with bleeding or clotting disorders, or those currently taking blood thinners.
* Participants currently taking beta-agonist inhalers i.e. Ventolin (at least not in the last 24 hours).
* Females who are pregnant, confirmed by a pregnancy test.
* Females who have are less than 1 year postpartum or are breastfeeding.
* Females who are post-menopausal.
* Participants that are classified as obese (body mass index \> 30 kg ⋅ m2).
* Have a history of smoking regularly in the last 6 months (but nicotine substitutes (i.e. patch, gum) are not an exclusion criteria).
* Those with a known allergy to sulfites, or other components of the supplied solution of study drugs.
* Participants taking medications that are contraindicated with any of the study drugs, such as monoamine oxidase (MAO) inhibitors or tricyclic antidepressants.
* Participants who have not adhered to the pre-testing guidelines related to diet, alcohol or exercise will not be excluded, but will be rescheduled for a different day. This is to reduce experimental variability.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
40 Years
Study:
NCT05997732
Study Brief:
Protocol Section:
NCT05997732