Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 1:16 PM
Ignite Modification Date:
2025-12-24 @ 1:16 PM
NCT ID:
NCT03758495
Eligibility Criteria:
Inclusion Criteria:
(All)
* Veterans
* 18-65 years of age
* Negative metal screen for MR scanning
* Corrected to normal vision
Inclusion Criteria (patients):
* Meet criteria for SZ or MDD as assessed using the Structured Clinical Interview for DSM (SCID), with a consensus diagnosis between trained research staff member and an attending psychiatrist or psychologist.
* Stable medication regime for \> 1 month
Exclusion Criteria:
(All)
* Past or present neurological problems (including seizures and head trauma resulting in neurological or cognitive sequelae)
* Loss of consciousness (LOC) greater than 30 minutes or any LOC with neurologic sequelae
* Major medical conditions (e.g., significant hypertension, diabetes not controlled by diet alone, seizure disorders, treatment with anticonvulsant medication, endocrine disorders, significant cardiac pathology)
* Substance abuse within three months of participation or any history of substance dependence
* History of HIV risk behaviors
* Known claustrophobia
* Pregnancy. If the participant cannot rule out pregnancy, a pregnancy urine test will be conducted moments before scanning.
* Uncorrected vision as assessed by the Snellen chart.
Exclusion criteria (patients only):
\- Any primary Diagnostic and Statistical Manual Diploma in Social Medicine (DSM) Axis I diagnosis other than SZ or MDD
Exclusion criteria (controls only):
* Any past or present DSM Axis I diagnosis
* Chronic treatment with medication that affects cognitive function
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
65 Years
Study:
NCT03758495
Study Brief:
Protocol Section:
NCT03758495