Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 1:16 PM
Ignite Modification Date:
2025-12-24 @ 1:16 PM
NCT ID:
NCT00440895
Eligibility Criteria:
Inclusion Criteria:
* Patient with acute myocardial infarction eligible for rescue PCI within 24 hrs of symptoms.
* Failed thrombolysis (defined as less than 50% reduction of ST-elevation at 90 min ECG in the lead with previous maximal ST-segment elevation).
* Patient \> 18 years old.
* Patient and treating interventional cardiologist agree for randomization.
* Patient will be informed of the randomization process and will sign an informed consent.
* Diagnostic and therapeutic intervention performed through transradial/transulnar approach.
* The culprit lesion in a native coronary artery can identified and is suitable for immediate angioplasty and stent implantation.
Exclusion Criteria:
* Age \> 75 years old
* Body weight \< 65 kg
* Concurrent participation in other investigational study
* Intolerance or allergy to ASA, clopidogrel or ticlopidine precluding treatment for 12 months
* Any significant blood dyscrasia, diathesis or INR \> 2.0.
* Any clinical contraindication to abciximab administration i.e. known structural intracranial lesion, thrombocytopenia (\< 100,000), hemoglobin level \< 10 g/dl
* Patient has received more than one dose of thrombolytic within 24 hours of symptoms
* Previous treatment with glycoproteins IIb-IIIa inhibitors within 30 days
* Perceived increased risk of intracranial or severe bleeding i.e. previous stroke/TIA, alteration of consciousness, recent trauma or major surgery.
* Uncontrolled high blood pressure i.e. systolic blood pressure ≥ 180 mmHg and/or diastolic blood pressure ≥ 100 mmHg.
* Life expectancy less than 6 months owing to non-cardiac cause
* Evident cardiogenic shock
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
75 Years
Study:
NCT00440895
Study Brief:
Protocol Section:
NCT00440895