Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 9:45 PM
Ignite Modification Date:
2025-12-24 @ 9:45 PM
NCT ID:
NCT01647932
Eligibility Criteria:
Inclusion Criteria:
* History of chronic heart failure
* Admission for acute decompensated heart failure
* There is no prespecified inclusion criterion with respect to heart failure etiology and/or ejection fraction
* Receipt of an oral loop diuretic for at least 1 month before hospitalization, at a dose between 80 mg and 240 mg daily in the case of furosemide and an equivalent dose in the case of a different loop diuretic (20 mg of torasemide or 1 mg of bumetanide was considered to be equivalent to 40 mg of furosemide)
Exclusion Criteria:
* Other etiologies of fluid overload different from heart failure
* Hyponatremia: any symptomatic sodium value or a sodium level below 125mmol/l
* Unstable patients: acute coronary syndrome, cardiogenic shock or ICU admission.
* Patients requiring inotropic agents or renal replacement therapies
* Life expectancy \< 6 months
* Prior treatment with thiazide-type diuretics
* Aldosterone antagonists are permitted if the patient had been taking them on a long-term basis (at least 30 days before randomisation)
* Pregnancy or breastfeeding period
* Active alcoholism and/or other substance abuse
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT01647932
Study Brief:
Protocol Section:
NCT01647932