Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 9:44 PM
Ignite Modification Date:
2025-12-24 @ 9:44 PM
NCT ID:
NCT00874432
Eligibility Criteria:
Inclusion Criteria:
* Age \> 60 years
* BP 120/80 or higher \*(bps will be checked weekly first 4 weeks to ensure \< 130/80 - IF bp remains \> 130/80 we will administer other bp meds per JNC VII guidelines)
* CKD stage 3 (GFR 30 - 59 ml/min) for CKD group; no CKD for control group
Exclusion Criteria:
* Known significant CVD (history of Myocardial infarction (MI), recurrent stroke, or New York Heart Association (NYHA) class III or greater).
* Serum potassium \> 5.2 meq/L
* Known allergy or hypersensitivity to ACE inhibitor or ARB
* Female of childbearing age not practicing contraception
* Current treatment with an Angiotensin Converting Enzyme Inhibitors (ACE-I) or Angiotensin-Receptor Blockers (ARB) (Note: can participate if on ACE-I after 6 week washout period)
* History of ACE-I induced angioedema
* History of angioedema, hereditary or idiopathic
* Persons lacking consent capacity
* 500 mg/dL proteinuria on 2 consecutive spot urine protein/creat ratios
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
60 Years
Maximum Age:
89 Years
Study:
NCT00874432
Study Brief:
Protocol Section:
NCT00874432