Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 1:15 PM
Ignite Modification Date:
2025-12-24 @ 1:15 PM
NCT ID:
NCT00189995
Eligibility Criteria:
Inclusion Criteria:
* schizophrenic, schizoaffective, or schizophreniform according to DSM-IV
* treatment-resistant
* presenting pathologic violent-aggressive behavior on admission
* at risk for self damage
* age: 18-65
* patient is not participating in any other study at time of this study
* minimal score of 70 on PANSS
* prior resistance to at least 2 different classes of neuroleptics
* OAS scores of at least 4 points in physical aggression sections and at least 2 points in verbal aggression section
Exclusion Criteria:
* neutropenia or any other abnormal CBC result
* myeloproliferative disease
* chronic physical diseases such as liver, renal or cardiac diseases
* history of alcohol or drug abuse
* history of drug induced granulocytopenia/agranulocytosis
* alcoholic/drug psychosis or intoxication
* carbamazepine or other bone marrow suppressor treatment
* uncontrolled epilepsy
* paralytic ileus
* hypersensitivity to clozapine
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
65 Years
Study:
NCT00189995
Study Brief:
Protocol Section:
NCT00189995