Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 1:14 PM
Ignite Modification Date:
2025-12-24 @ 1:14 PM
NCT ID:
NCT05874895
Eligibility Criteria:
Inclusion Criteria:
* diagnosis of septic shock at admission to ICU
* sepsis or suspicion of sepsis
* noradrenaline support required in order to maintain mean arterial pressure ≥ 65 mmHg
* serum lactate ≥ 2 mmol/L
Exclusion Criteria:
* patients \<18 years of age
* pregnant women with septic shock, in whom the pregnancy has been preserved
* patients with a history of heart failure with NYHA (New York Heart Association) classification ≥ III
* patients with a history of thromboembolic events
* patients with septic shock transferred from another department/hospital, if the length of stay at the previous workplace exceeded 72 hours
* patients with septic shock and an inauspicious prognosis, or in the phase of withdrawal of treatment
* patients with uncontrolled infection
* patients with septic shock who lack informed consent
* patients with septic shock, in whom the SOFA score decreased by more than 50% during the day following the withdrawal of noradrenaline (i.e. a subgroup of patients with a rapid improvement of the clinical course after the resolution of septic shock).
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT05874895
Study Brief:
Protocol Section:
NCT05874895