Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 9:40 PM
Ignite Modification Date:
2025-12-24 @ 9:40 PM
NCT ID:
NCT00502632
Eligibility Criteria:
Inclusion Criteria:
* Age \> 1 year and \< 16 years
* Respiratory infection (pneumonia or lung abscess)
* Effusion occupying at least 1/3 of hemithorax on chest X-ray
* Complicated effusion (presence of at least one of the following):
* Hyperechoic pleural fluid on chest US scan
* Loculated collection on chest US or CT scan
* Purulent pleural fluid
* Positive culture or Gram stain on pleural fluid
Exclusion Criteria:
* Non parapneumonic effusion
* Immunodeficiency
* Neurological impairment
* Suspected or proven allergy to Urokinase or Dornase alfa
* Suspected or documented bronchopleural fistula
* Impaired coagulation (INR\>2), haemorrhage, high risk for bleeding
* Thoracic surgical procedure (e.g. thoracoscopy, mini-thoracotomy) already performed
* Chest drain inserted since 6 or more days
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
1 Year
Maximum Age:
16 Years
Study:
NCT00502632
Study Brief:
Protocol Section:
NCT00502632