Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 9:24 PM
Ignite Modification Date:
2025-12-24 @ 9:24 PM
NCT ID:
NCT04484532
Eligibility Criteria:
Inclusion Criteria:
* Subject or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to undergoing any investigational biospecimen (blood) collection procedure
* Willing to undergo seasonal influenza vaccination with Fluzone high dose at Roswell Park Cancer Institute within 2 weeks of enrollment of this study
* Estimated survival of 8 weeks or more following enrollment on the study
Exclusion Criteria:
* Uncontrolled intercurrent illness including, but not limited to, ongoing or active influenza infection or influenza-like-illness
* Women who are attempting pregnancy or known to be pregnant by clinical history or nursing female subjects
* Unwilling or unable to follow protocol requirements
* Use of prednisone \> 10 mg/day (or its equivalent for other steroids) for \> 2 weeks immediately prior to receiving seasonal influenza vaccination
* Received dose of seasonal influenza vaccination prior to enrollment
* Participation at the time of study enrollment in another clinical trial investigating immunotherapeutic agents (like anti-PD1 or anti-PDL1 or anti-CTLA4 antibodies or vaccines); concurrent participation in an observational/non-interventional study or an interventional study investigating tyrosine kinase inhibitor or other targeted agents use is acceptable
* Inability to receive seasonal influenza vaccine due to prior hypersensitivity to eggs, chicken proteins, or any of the vaccine components
* History of a life-threatening reaction to influenza vaccination or to a vaccine containing similar substances
* Personal history of Guillain-Barre syndrome
* Any condition which in the investigator's opinion deems the subject an unsuitable candidate to receive annual influenza vaccination or may potentially affect the response to influenza vaccination
* Adults unable to consent, individuals who are not yet adults (infants, children, and teenagers), women who are known to be pregnant, attempting pregnancy, or nursing women, and prisoners will be excluded from the study
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
40 Years
Study:
NCT04484532
Study Brief:
Protocol Section:
NCT04484532