Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 9:24 PM
Ignite Modification Date:
2025-12-24 @ 9:24 PM
NCT ID:
NCT00529932
Eligibility Criteria:
Inclusion Criteria:
* Primary PCI for acute STEMI between 2-24 hours after onset of chest pain.
* ST-segment elevation \>=2mm in \>=3 adjacent leads.
* Presence of severe hypokinesia and/or akinesia in \>=2 adjacent segments on echocardiogram at 48-72 hrs after primary PCI.
* Age between 20 and 75 years.
Exclusion Criteria:
* Pregnant or lactating.
* Prior history of myocardial infarction before index event.
* Decompensated congestive heart failure.
* Pre-existent LV dysfunction (EF \<45% prior to admission)
* Cardiomyopathy.
* Previous cardiac surgery.
* Congenital heart disorder.
* Serum creatinine \>200 Mmol/L.
* Presence of permanent pacemaker or implantable defibrillator.
* Contraindication to bone marrow aspiration.
* History of malignancy within 5 years except curatively treated basal cell carcinoma, squamous cell carcinoma and/or cervical carcinoma.
* Sustained or inducible VT \>48 hours post primary PCI.
* Three vessel coronary artery disease necessitating intervention within 4 months.
* Immune compromise including chronic human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV) infection.
* Presence of chronic systemic inflammatory disorders.
* Previous autologous or allogeneic bone marrow or peripheral stem cell transplant or prior solid organ transplantation.
* Low hemoglobin, white blood cell, absolute neutrophil and/or platelet count.
* Any condition associated with a life expectancy of less than 6 months.
* Participation in unrelated research involving investigational pharmacological agent(s) 30 days before planned dosing.
* Current alcohol or drug abuse.
* Inability to provide written informed consent.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
20 Years
Maximum Age:
75 Years
Study:
NCT00529932
Study Brief:
Protocol Section:
NCT00529932