Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 9:19 PM
Ignite Modification Date:
2025-12-24 @ 9:19 PM
NCT ID:
NCT03631004
Eligibility Criteria:
Inclusion criteria:
* Patients submitted to medium and large surgeries in the thoracic or abdominal region (mastectomies, breast plastic, hysterectomies, annexectomies, gynecological pelvic surgeries, colectomies, rettosigmoidectomies) under general anesthesia
* Patients aged between 18 and 60 years
* Patients considered to be at high risk for PONV according to the Apfel scale (Apfel 3 or 4)
* Patients with a history of chemotherapy-induced nausea and vomiting.
Exclusion criteria:
* Pregnancy or Lactation
* Current use of typical anti-psychotic medications or atypical
* History of allergy to olanzapine
* Myocardial infarction or unstable angina in the 6 months prior to the day of surgery planning
* History of severe ventricular arrhythmia (eg, VT or VF)
* Heart Failure Class II or greater second NYHA
* Postural hypotension or vasovagal syncope in the 6 months prior to the day of surgery planning
* Narrow angle glaucoma
* Parkinson's disease
* Dementia
* Inability to swallow medicines
* QT interval history greater than 450ms or torsades de pointes
* Patient does not want to participate in the study
* Videolaparoscopy surgery
* Contraindication for neuraxial block
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
60 Years
Study:
NCT03631004
Study Brief:
Protocol Section:
NCT03631004