Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 1:09 PM
Ignite Modification Date:
2025-12-24 @ 1:09 PM
NCT ID:
NCT06083961
Eligibility Criteria:
Inclusion Criteria:
* Non-cardioembolic Stroke
* Acute Ischemic stroke within 7 days of symptom onset (confirmed by CT or MRI)
* Age 19 and above
* Significant stenosis associated with atherosclerosis in major intracranial / extracranial vessels.
* National Institutes of Health Stroke Scale(NIHSS) score of 15 or less at admission
* Patients with the capacity to consent for participation in the clinical trial.
Exclusion Criteria:
* Presence of high-risk factors for cardioembolism
* Risk of ischemic stroke due to thrombosis from other causes
* Patients with hemorrhagic stroke, brain tumors, or brain abscesses
* Patients unable to take statins or PCSK9 inhibitors
* Pre-stroke mRS score of 3 or higher
* Severe liver failure (liver enzyme \> 3 times the upper normal limit) or renal failure (serum Creatinine \> 2mg/dL or estimated glomerular filtration rate \< 30 mL/min/1.73m2)
* Anemia (hemoglobin \< 8mg/dL) or thrombocytopenia (platelet count \< 100K)
* Uncontrolled diabetes not managed by medication or insulin
* Pregnant or breastfeeding patients
* Patients already receiving PCSK-9 inhibitors
* Patients deemed inappropriate for participation in the clinical trial by the investigator for other reasons.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
19 Years
Study:
NCT06083961
Study Brief:
Protocol Section:
NCT06083961