Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 9:12 PM
Ignite Modification Date:
2025-12-24 @ 9:12 PM
NCT ID:
NCT06987604
Eligibility Criteria:
Inclusion Criteria:
* Age ≥ 18 years
* Diagnosis of acute liver failure (ALF) or acute-on-chronic liver failure (ACLF) Presence of hyperammonemia, defined as: Arterial ammonia \>72 μmol/L and hepatic encephalopathy grade ≥2 or Arterial ammonia \>100 μmol/L regardless of encephalopathy grade
* Indication for continuous renal replacement therapy (CRRT), as determined by the attending medical team
* Informed consent provided by the patient or legal representative
Exclusion Criteria:
* Age \< 18 years
* Pregnancy
* Diagnosis of acute liver failure (ALF) in the context of severe hemodynamic instability
* ALF secondary to ischemic hepatic injury
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT06987604
Study Brief:
Protocol Section:
NCT06987604