Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 9:11 PM
Ignite Modification Date:
2025-12-24 @ 9:11 PM
NCT ID:
NCT02680704
Eligibility Criteria:
Inclusion Criteria:
* Patients with severe brain injury (GCS 8 or less)
* Receiving mechanical ventilation
* Receiving intracranial pressure monitoring
Exclusion Criteria:
* Esophageal varices
* Esophageal trauma
* Recent esophageal surgery
* Coagulopathy (Platelets \< 80k or INR\> 2 )
* Other contraindication for esophageal manometry
* Already receiving PEEP \> 15 cmH2O at enrollment
* Intracranial hypertension (defined as ICP \> 20 mmHg)
* Decompressive hemi-craniectomy
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT02680704
Study Brief:
Protocol Section:
NCT02680704