Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 9:08 PM
Ignite Modification Date:
2025-12-24 @ 9:08 PM
NCT ID:
NCT00149604
Eligibility Criteria:
Inclusion Criteria:
* postmenopausal women
* aged 50-70 yr
* healthy, as determined by medical history, physical examination, blood chemistries, and a graded exercise stress test with monitoring of blood pressure and ECG
* good cognitive function.
Exclusion Criteria:
* contraindications to estrogen or raloxifene treatment, including history of or active breast cancer or other estrogen-dependent neoplasms, acute liver disease, undiagnosed vaginal bleeding, and active or history of blood clotting disorders
* mild or more severe cognitive impairment, indicated by a MMSE score \<26
* clinically significant abnormal resting electrocardiogram (ECG), angina and/or ECG evidence of acute myocardial ischemia during a maximal exercise stress test
* resting blood pressure above 150 mmHg systolic or 90 mmHg diastolic
* left bundle branch blocks, A-V block greater than first degree, clinically significant arrhythmias
* congestive heart failure
* pulmonary emboli in the previous 6 months
* aortic stenosis
* chronic infections
* orthopedic or other problems that would interfere with participation in the exercise program
Healthy Volunteers:
True
Sex:
FEMALE
Minimum Age:
50 Years
Maximum Age:
70 Years
Study:
NCT00149604
Study Brief:
Protocol Section:
NCT00149604