Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 9:07 PM
Ignite Modification Date:
2025-12-24 @ 9:07 PM
NCT ID:
NCT06141304
Eligibility Criteria:
Inclusion Criteria:
* The age of the patients is ≥ 14 and ≤ 60 years old;
* Those with relapsed acute leukemia after allo-HSCT with bone marrow blasts less than 50%;
* The expected survival exceeds 3 months;
* At least 100 days post transplantation, and the immunosuppressants were discontinued;
* Those with no significant abnormalities of the main organ function: creatinine ≤ 176.8 μ Mol/L, bilirubin ≤ 51.3 μ Mol/L, aspartate aminotransferase and alanine aminotransferase ≤ 2.5 times the normal upper limit;
* Sign an informed consent form.
Exclusion Criteria:
* Those with patient-specific human leukocyte antigen (HLA) loss at relapse;
* Those with active graft-versus-host disease;
* Those with severe infection;
* Those with organ function failure;
* Those with an Eastern Cooperative Oncology Group (ECOG) score more than 2 points;
* Those who are allergic to experimental drugs;
* Those who use other anti-leukemia therapies, such as radiotherapy, cellular immunotherapy, or Chinese medical herbs;
* Those participate in other clinical trials simultaneously;
* Those having mental illness or other illnesses that cannot fully comply with treatment or follow-up requirements;
* Those with extramedullary leukemia;
* Those with other conditions that researchers evaluate who are not proper to participate in this clinical trial.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
14 Years
Maximum Age:
60 Years
Study:
NCT06141304
Study Brief:
Protocol Section:
NCT06141304