Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 9:06 PM
Ignite Modification Date:
2025-12-24 @ 9:06 PM
NCT ID:
NCT03005704
Eligibility Criteria:
Inclusion Criteria:
* Healthy subjects
* At least 18 years of age
* No history of cardiovascular disease
* Not taking antiplatelet therapy prior to participation
Exclusion Criteria:
* Known thrombocytopenia, other coagulation disorder such as von Willebrand's disease, haemophilia
* Allergy or intolerance to ticagrelor or aspirin (if known)
* Consumption of drugs within the preceding fourteen days that potentially can interfere with metabolism of ticagrelor through CYP3A4, CYP3A or P-glycoprotein (eg, ketoconazole, clarithromycin, nefazodone, ritonavir, atazanavir, diltiazem, amprenavir, aprepitant, erythromycin, fluconazole, verapamil, rifampicin, dexamethasone, phenytoin, carbamazepine, phenobarbital, cyclosporine, simvastatin, atorvastatin, tolbutamide, digoxin)21
* Previous transfusion or pregnancy (because of potential alloimmunisation)
* Pregnant or trying to conceive, or breastfeeding
* Unable or unwilling to give written informed consent
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT03005704
Study Brief:
Protocol Section:
NCT03005704