Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 7:51 PM
Ignite Modification Date:
2025-12-24 @ 7:51 PM
NCT ID:
NCT06968104
Eligibility Criteria:
Inclusion Criteria:
* Diagnosis of Post-COVID Syndrome (persistent symptoms \> 3 months post-infection)
* Diagnosis of ME/CFS (following Canadian Consensus Criteria) Aged 18-65
* Moderate to severe fatigue (Fatigue Severity Scale ≥ 5)
* Stable medical regimen for at least 3 months
* Participants who are willing to follow the treatment protocol, and able to comply with remote monitoring.
* Sufficient proficiency in German or English language
Exclusion Criteria:
* Pacemaker or other implanted electronic or metallic devices
* Neurological or psychiatric disorders unrelated to ME/CFS or Post-COVID Syndrome
* Pregnancy or breastfeeding
* History of vagus nerve damage or significant ear injury
* Previous or ongoing use of taVNS
* Bradycardia (resting heart rate below 60 beats per minute)
* permanent jewelry at close proximity to the ear tragus;
* Known severe coronary disease or recent heart attack (within 5 years)
* Medications that may influence autonomic function, HRV, and fatigue
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
65 Years
Study:
NCT06968104
Study Brief:
Protocol Section:
NCT06968104