Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 7:50 PM
Ignite Modification Date:
2025-12-24 @ 7:50 PM
NCT ID:
NCT00362804
Eligibility Criteria:
Inclusion Criteria:
* has been on an antipsychotic medication for at least 3 months and achieved the maximum dose vis à vis tolerability/side effects.
* Partial response to antipsychotic medication (CGI \> 4; BPRS \[Anchored, 18-item\] total \> 30; single item score \> 4 on 2 positive symptom items)
* has been on at least 2 previous antipsychotic trials of 4-6 weeks in duration at a dose reaching 400-600 mg chlorpromazine (or equivalent) with no clinical improvement
Exclusion Criteria:
* age \< 18 or \> 65
* previous documentation of hypersensitivity to tetrabenazine
* SCID criteria for a current depressive episode
* MAOI administration within 2 weeks of tetrabenazine treatment
* concomitant desipramine use
* diagnosis of idiopathic Parkinson's disease and/or levodopa treatment
* current unstable medical illness and current substance abuse
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
65 Years
Study:
NCT00362804
Study Brief:
Protocol Section:
NCT00362804