Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 7:49 PM
Ignite Modification Date:
2025-12-24 @ 7:49 PM
NCT ID:
NCT00541203
Eligibility Criteria:
Inclusion Criteria:
1. Chest pain or other symptoms suggestive of coronary artery disease.
2. Pharmacologic/exercise stress test with SPECT within the past 3 months.
3. "Discordant" clinical and stress results as outlined above.
4. Scheduled to undergo cardiac catheterization.
5. Able to provide informed consent.
6. Age equal to or greater than 18 years.
Exclusion Criteria:
1. Presence of pre-existing CAD (prior myocardial infarction, prior angiographic evidence of significant coronary artery disease, prior coronary bypass surgery) or cardiomyopathy (ejection fraction \< 45%)
2. History of hypertension with severe left ventricular hypertrophy, history of cor pulmonale.
3. Renal insufficiency (creatinine ≥1.6) or renal failure requiring dialysis.
4. Inability or refusal to provide informed consent.
5. Psychological unsuitability or extreme claustrophobia.
6. Pregnancy or unknown pregnancy status.
7. Age less than 18 years.
8. Patients with known allergy to iodinated contrast, unable to tolerate pre-medication.
9. Inability to tolerate beta-blockers, including those with COPD or asthma requiring maintenance inhaled bronchodilators or steroids, complete heart block, second-degree atrioventricular block.
10. Computed tomography imaging, or contrast administration, within the past 48 hours.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT00541203
Study Brief:
Protocol Section:
NCT00541203