Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 7:48 PM
Ignite Modification Date:
2025-12-24 @ 7:48 PM
NCT ID:
NCT02779803
Eligibility Criteria:
Inclusion Criteria:
* Internal carotid artery or middle cerebral artery occlusion
* Transient ischemic attack (TIA) or ischemic stroke in the ipsilateral hemisphere within 30 days in patients who are either
* hospitalized unstable patients with crescendo or postural TIA's, OR
* Multiple TIA's, limb-shaking TIA's, and/or cognitive decline despite medical therapy\*
* Evidence of ipsilateral impaired cerebrovascular reserve on physiological testing (e.g. Diamox challenge SPECT)
* Modified Rankin Score (mRS) \>3
* Language comprehension intact
* Age 18-85 years \* failure of medical therapy must include at least failure on a regimen of antiplatelets and statins.
Exclusion Criteria:
* Moya-moya syndrome
* Known heart disease likely to cause cerebral ischemia
* Prosthetic Valves
* Atrial Fibrillation
* Infective endocarditis
* Left atrial or ventricular thrombus
* Sick sinus syndrome
* Cardiac myxoma
* Cardiomyopathy with ejection fraction \< 25%
* Any condition likely to lead to death within 2 years
* Pregnancy
* Allergy or contraindication to aspirin
* Uncontrolled diabetes mellitus (FBS \> 300 mg%/16.7 mmol/L)
* Uncontrolled hypertension (systolic BP\>180, diastolic BP \>110), other than induced for control of pressure dependent symptoms
* Uncontrolled hypotension (diastolic BP \<65)
* Unstable angina
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
85 Years
Study:
NCT02779803
Study Brief:
Protocol Section:
NCT02779803