Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 7:48 PM
Ignite Modification Date:
2025-12-24 @ 7:48 PM
NCT ID:
NCT03657303
Eligibility Criteria:
Group 1 Inclusion Criteria:
* Meets ACR criteria for OA Kellgren-Lawrence grade 2-3 on knee radiograph
* Neutral alignment
* Single symptomatic joint
* Aged 40-60 years old
* Ambulatory and in good general health
* Knee able to fit inside in-vivo knee coil (approx. 18 cm diameter)
Group 2 Inclusion Criteria:
* No current symptoms of knee pain or stiffness or other clinical features of OA
* Aged 40-60 years old
* Written consent to participate in the study
* Ambulatory and in good general health
* Knee able to fit inside in-vivo knee coil (approx. 18 cm diameter)
Exclusion Criteria for both groups:
* History of ipsilateral lower limb fracture
* History of ipsilateral lower limb surgery (including arthroscopy)
* Metabolic bone disease
* Inflammatory arthritis
* Haematological malignancy
* Paget's disease
* Bone metastases
* Contraindication to MR imaging (e.g. pacemaker, severe claustrophobia)
* No pregnant patients will be included
* Unable to consent
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
40 Years
Maximum Age:
60 Years
Study:
NCT03657303
Study Brief:
Protocol Section:
NCT03657303