Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 7:46 PM
Ignite Modification Date:
2025-12-24 @ 7:46 PM
NCT ID:
NCT00055003
Eligibility Criteria:
* INCLUSION CRITERIA:
All subjects will be between 18 and 50 years old.
Male and female subjects will be included.
Females will be studied in the luteal phase.
All subjects must be able to give written informed consent prior to participation in this study.
EXCLUSION CRITERIA:
Children less than 18.
Individuals with any major medical or neurological disorder, or taking any medication within 3 weeks of scanning that is likely to influence CBF or metabolism, or having any endocrine condition expected to be associated with abnormal HPA axis function.
Individuals who meet DSM-IV criteria for alcohol and/or substance abuse within 1 year prior to screening or lifetime history of substance dependence.
Individuals with a current or past history of other axis I psychiatric disorders.
Individuals with first-degree family members with current or past history of mood disorder.
Women of childbearing potential who have a positive pregnancy test who are currently nursing.
Individuals who have experienced serious suicidal ideation or attempt within the past 6 months.
Smokers are ineligible to participate.
Women with irregular menstrual cycles or taking oral contraceptives.
Those with a weight greater than 100 kgs.
Those with previous allergic reactions or hypersensitivity to hydrocortisone.
General exclusions for MRI imaging, such as having had a cardiac pacemaker or ferromagnetic object implanted through surgical intervention or accident, e.g. shrapnel.
Those with a history of peptic ulcer disease.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
50 Years
Study:
NCT00055003
Study Brief:
Protocol Section:
NCT00055003