Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 7:44 PM
Ignite Modification Date:
2025-12-24 @ 7:44 PM
NCT ID:
NCT05026203
Eligibility Criteria:
Inclusion Criteria:
* over 20 years old
* depression was diagnosed by a psychiatrist and having MADRS \>= 25
* depression treated with 2 optimal dosage of antidepressants for 4 weeks and one psychotherapy
* stable dosage of current medications for 4 weeks
* fluently Thai
Exclusion Criteria:
* secondary depression
* PTSD
* current pregnancy
* history of increased intracranial hemorrhage, increased intracranial pressure, severe head injury, abnormal thyroid function, angina, heart failure, arrhythmia, aneurysm, uncontrolled hypertension, chronic lower tract respiratory disease, myasthenia gravis, glaucoma, dementia, acute porphyria, or cystitic (within 3 months prior to recruitment)
* allergy to ketamine or midazolam
* history of substance use disorder within 1 year prior to recruitment
* history of psychosis within 3 months
* history of bipolar disorder
* BMI over 35
* frail medical condition
* currently ECT or TMS
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
20 Years
Study:
NCT05026203
Study Brief:
Protocol Section:
NCT05026203