Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 7:41 PM
Ignite Modification Date:
2025-12-24 @ 7:41 PM
NCT ID:
NCT07101003
Eligibility Criteria:
Inclusion Criteria:
* Age between 18-40 years.
* Males/Females.
* Straight single canaled permanent teeth:
* Non-Vital pulps.
* Negative response to cold pulp tester (ethyl chloride spray\*).
* Absence of spontaneous pain.
* Chronic apical periodontitis with negative response to percussion
* Slight widening in the periodontal membrane space or with periapical radiolucency not exceeding 2\*2 mm radiographically. The Periapical Index (PAI) score by Ørstavik is 2 or 3 (Ørstavik et al., 1986 43)
* Systemically healthy patients (ASA I or II)
* No anti-inflammatory or antibiotic medications taken in the past month
* Patients' acceptance to participate in the trial.
* Patients who can understand pain scale and can sign the informed consent (Appendix I).
* Patients' acceptance to participate in the trial.
Exclusion Criteria:
* Medically compromised patients having significant systemic disorders. (ASA III or IV).
* Teeth with swelling or fistulous tract.
* Teeth with acute or chronic periapical abscess.
* Mobility Grade II or III.
* Previous root canal therapy.
* Non-restorable teeth.
* Immature teeth.
* Pregnant females.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
40 Years
Study:
NCT07101003
Study Brief:
Protocol Section:
NCT07101003