Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 7:34 PM
Ignite Modification Date:
2025-12-24 @ 7:34 PM
NCT ID:
NCT00963703
Eligibility Criteria:
Inclusion Criteria:
* Patients with documented rheumatoid arthritis by ACR criteria
* Disease duration \< 5 years
* May have previously been treated with methotrexate,hydroxychloroquine or sulfasalazine, either as a single DMARD or in combination
* Tender joint count \>= 6, swollen joint count \>= 6, and one must be a knee
* Corticosteroids \<= 10 mg per day permitted on stable doses for at least 4 weeks
* Patients must consent to 2 arthroscopic synovial biopsy procedures
Exclusion Criteria:
* History of severe allergic or anaphylactic reactions to monoclonal antibodies
* Previous treatment with Rituximab
* Previous treatment with Arava
* Injected with steroids within 4 weeks of day 1 of study
* Treatment with any investigational agent within 4 weeks of day of study
* Any severe or significant medical condition or disease or known active infection
* Pregnancy or nursing at present
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT00963703
Study Brief:
Protocol Section:
NCT00963703