Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 7:33 PM
Ignite Modification Date:
2025-12-24 @ 7:33 PM
NCT ID:
NCT07006103
Eligibility Criteria:
Inclusion Criteria:
* Patients over 18 years of age with a diagnosis of EC diagnosed by histological biopsy and surgically treated sequentially in the participating centers in the last 5 years with clinical follow-up.
* Patients over 18 years of age, diagnosed with CE III-IV by histological biopsy, not susceptible to surgical treatment in each institution during the last 5 years in clinical follow-up. Cases with a diagnosis of carcinosarcoma (a rare subtype of endometrial carcinoma with sarcomatous transdifferentiation) are included.
* Material blocks fixed in formalin and embedded in paraffin with a tumor volume in the paraffin block of at least 1 cm3
Exclusion Criteria:
* The following uterine neoplasms will be excluded:
* Biphasic tumors (epithelial-mesenchymal) such as adenosarcoma.
* Mesenchymal neoplasms such as endometrial stromal sarcoma and leiomyosarcomas.
* Others: primary lymphoproliferative processes of the uterine body; neuroendocrine tumors; Gestational trophoblastic disease, secondary lesions either of the genital tract (example: cervical carcinomas with extension to the endometrium) or of distant sites (breast cancer metastasis).
* Patients with synchronous endometrial and ovarian carcinoma
* For technical reasons, they will be excluded
* tumors smaller than 0.2 cm in which sufficient material cannot be obtained for immunohistochemical and molecular biology determinations.
* Tumors with severe artifacts due to poor processing, such as autolysis.
* Samples with low-quality DNA
* Patients operated on outside participating centers.
* Patients under 18 years of age.
* Patients with primary non-surgical treatments (neoadjuvant chemotherapy).
Healthy Volunteers:
False
Sex:
FEMALE
Minimum Age:
18 Years
Study:
NCT07006103
Study Brief:
Protocol Section:
NCT07006103