Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 7:30 PM
Ignite Modification Date:
2025-12-24 @ 7:30 PM
NCT ID:
NCT02240303
Eligibility Criteria:
Inclusion Criteria:
* Age 65 years and older
* Willingness to participate in all study procedures
* Cognitively intact as defined by 3MS score \> 80
Exclusion Criteria:
* Failure to provide informed consent;
* Contraindications to MRI, such as claustrophobia, heart pacemaker / defibrillator, heart valve prosthesis, aneurysm clip, metallic stent, neurostimulation system, cochlear implants or inner ear prosthesis, insulin pump or other infusion pump, metal slivers in the orbital area/eye socket
* Active treatment for cancer or history of cancer in the past year
* Severe cardiac disease, including New York Heart Association (NYHA) Class III or IV congestive heart failure, clinically significant aortic stenosis, history of cardiac arrest or stroke, use of a cardiac defibrillator, or uncontrolled angina;
* Previous stroke with upper and/or lower extremities involvement within the last 6 months
* History of life-threatening cardiac arrhythmias, stroke, severe Parkinson's disease or severe neurological disorders likely to interfere with physical function
* Renal disease requiring dialysis
* Lung disease requiring steroids
* Inability to reliably rate pain intensity
* Current use of tobacco products
* Uncontrolled hypertension (BP of greater than 150/99 mm Hg)
* Serious systemic disease that restrict normal daily activities
* Neurological problems with significant changes in somatosensory and pain perception at the intended stimulation sites,
* Uncontrolled psychiatric condition (e.g., experiencing symptoms of schizophrenia, bipolar disorder, etc.) or hospitalization within the preceding year for psychiatric illness
* Daily use of narcotic medication
* Lower extremity amputation
* Uncontrolled diabetes (self-reported medication use and/or HA1C value)
* A known diagnosis of dementia
* Inability to communicate because of severe hearing loss or speech disorder;
* Severe visual impairment, which would preclude completion of the assessments and/or intervention.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
65 Years
Study:
NCT02240303
Study Brief:
Protocol Section:
NCT02240303