Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 7:24 PM
Ignite Modification Date:
2025-12-24 @ 7:24 PM
NCT ID:
NCT02798003
Eligibility Criteria:
Inclusion Criteria:
* For cachectic patients: weight loss exceeds 5% of total body weight over the past 6 months, or \>2% when body mass index is \<20 kg/m2
* For non-cachectic patients: no weight loss of ≥5% during the last 6 months
* Non-small cell lung cancer or gastro-intestinal cancer, pathology proven or diagnosis of COPD consistent with the Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria
Exclusion Criteria:
* Contra-indications for fMRI examination (operation to your head or brain in the past; implanted electronic devices, for instance a pacemaker, neurostimulator, cochlear or hearing implant; insulin pump under your skin; Pregnant subjects, claustrophobia; pregnancy; metal parts in your body (except from teeth filling and connectors): implants; brain vessel clamps, prostheses, intra-uterine device, metal splinter in the eye, metal braces or other metal objects, permanent eye make-up)
* Psychiatric or other disorders likely to impact on informed consent
* Presence of brain metastasis (screening is not mandatory)
* Medical history of cerebrovascular accident, brain tumour, brain metastasis
* Previous radiotherapy to brain, both stereotactic and whole brain radiotherapy
* Memory problems
* Current use of tube feeding or parental nutrition
* Patients with an active second malignancy
* Patients unable to lie still for 2 hours
* Unable to complete the cognitive task
* Pre-existing swallowing difficulties
* Allergy to gluten-, milk- or wheat products
* Self-reported hyperthyroidism
* Self-reported diabetes mellitus
* Current use of appetite stimulant medications
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT02798003
Study Brief:
Protocol Section:
NCT02798003