Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 7:17 PM
Ignite Modification Date:
2025-12-24 @ 7:17 PM
NCT ID:
NCT06266403
Eligibility Criteria:
Inclusion Criteria:
Speakers with amyotrophic lateral sclerosis (ALS) (PALS-people with ALS)
* diagnosis of ALS following the revised EL Escorial criteria
* no history of other neurological conditions (e.g., stroke)
* no cognitive impairment assessed by Telephone Montreal Cognitive Assessment (mini MoCA)
* detectable speech disturbance according to the ALS Functional Rating Scale-Revised (ALSFRS-R)
* the ability to produce single words
* being a native speaker of American English (AE).
Age-matched Speakers
* passing the remote hearing screening
* having no known speech, language, or neurological disorders per self-report
* no cognitive impairment assessed by Telephone Montreal Cognitive Assessment (mini MoCA)
* being a functionally native monolingual speaker of American English.
Unfamiliar Interlocutors
* passing the remote hearing screening
* having no known speech, language or neurological disorders per self-report
* being a native monolingual speaker of American English
* having no experience communicating with people with dysarthria
* being between the ages of 18 and 40.
Exclusion Criteria:
* None - if volunteer meets the inclusion criteria, then they will be enrolled
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
90 Years
Study:
NCT06266403
Study Brief:
Protocol Section:
NCT06266403