Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 7:16 PM
Ignite Modification Date:
2025-12-24 @ 7:16 PM
NCT ID:
NCT04640103
Eligibility Criteria:
Inclusion Criteria:
1. ≥18 years old,diagnosed as gastric or colorectal cancer by pathology;
2. Diagnosed as a mismatch repair deficient by immunohistochemistry,or diagnosed as microsatellite instability-high by polymerase chain reaction(PCR) or next-generation sequencing(NGS);
3. Suitable for tumor radical resection;
4. Join this trial voluntarily,and could sign an informed consent form;
5. With good compliance.
Exclusion Criteria:
1. Do not use immunotherapy containing PD-1/PD-L1 antibody during the perioperative period;
2. Simultaneous diagnosis of dual primary tumors, and the second tumor cannot be resected radically, or the second tumor is not dMMR/MSI-H;
3. Complicate with uncontrollable immune system diseases;
4. Patients who need to use glucocorticoids and other immunosuppressive agents for a long time;
5. Patients who received live vaccines or live attenuated vaccines within 30 days before the medication, except for inactivated vaccines;
6. Those who cannot provide detailed medical records or cannot cooperate with follow-up.
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04640103
Study Brief:
Protocol Section:
NCT04640103