Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 7:14 PM
Ignite Modification Date:
2025-12-24 @ 7:14 PM
NCT ID:
NCT01433003
Eligibility Criteria:
Inclusion Criteria:
1. Age \> 18 year-old
2. First presentation of TTP/HUS
3. Meet all of the following diagnostic criteria:
* Platelet count \< 150 x 109 /L
* Microangiopathic haemolytic anaemia (blood film with presence of red blood cell fragmentation)
* LDH \> 1.25 X the upper limits of normal
* No alternative diagnosis
Exclusion Criteria:
1. Secondary TTP/HUS
2. Relapsing TTP/HUS
3. Hypersensitivity to blood product
4. Patient has received 2 or more plasma exchange treatment since symptom started over the last 1 week
5. Received medication, including cyclosporine, cyclophosphamide, rituximab for treatment of TTP/HUS
6. Other causes of thrombocytopenia than TTP/HUS
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT01433003
Study Brief:
Protocol Section:
NCT01433003