Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 7:10 PM
Ignite Modification Date:
2025-12-24 @ 7:10 PM
NCT ID:
NCT05875103
Eligibility Criteria:
Inclusion Criteria:
* For Cognitive cortical neurodegenerative diseases PATIENTS
* informed consentPatients between 40 and 85 years old,
* French native language,
* Social Security affiliation,
* Can read, write and count (up to 36) and knows the alphabet
* Assessed in Amiens University Memory Clinic for:
* Mild severity impairment (MMSE\> 19) or major severity impairment related to:
* AD according to Albert criteria and McKhann criteria
* DCL according to McKeith criteria
* FTLD according to Rascovsky criteria
* CBD according to Armstrong's criteria
* PSP according to Höglinger criteria
* For Stroke PATIENTS
* informed consent
* Patients between 40 and 85 years old,
* French native language,
* Social Security affiliation,
* Can read, write and count (up to 36) and knows the alphabet
* Having suffered a stroke, hospitalized in neurology, visualized by imaging
Exclusion Criteria:
* Mental retardation or guardianship
* Other current or past brain condition affecting cognition, including:
* Severe head trauma
* Epilepsy prior to stroke still requiring previous treatment
* Parkinson disease, multiple sclerosis
* Brain tumor or brain radiation therapy
* Current or past schizophrenia or psychosis
* Active or past psychiatric impairments requiring a stay\> 2 days in a specialized environment
* Contra indication to MRI
* Comorbidity with life expectancy \<1 year
* Comorbidity affecting cognition in particular:
* Alcohol (\> 3 glasses / day) or history of alcohol withdrawal syndrome
* Opiate or cocaine addiction or opiate withdrawal syndrome
* Renal failure (dialysis or creatinine clearance \<30)
* Hepatic failure (spontaneous INR\> 1.5 or PT \<60%)
* Respiratory failure requiring oxygen therapy
* Heart failure (orthopnea\> 2 pillows)
* Persistent vigilance disorder (NIHSS1a score ≤1)
* Cancer with paraneoplastic syndrome
* Treatment with gold salts, D Penicillamine or other treatment with cognitive effect
* Patient under guardianship or curators or private under public law
* Pregnant and / or lactating woman
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT05875103
Study Brief:
Protocol Section:
NCT05875103