Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 7:10 PM
Ignite Modification Date:
2025-12-24 @ 7:10 PM
NCT ID:
NCT06501703
Eligibility Criteria:
Inclusion Criteria:
* solitary-rooted lower premolar teeth with acute irreversible pulpitis and apical periodontitis who were in the age range between 18 and 40 years old.
* Each patient received root canal treatment in one session.
* restorable teeth with a normal periodontal score index of less than two
* severe preoperative pain (Vas score 3)
* discomfort response on biting/mastication or percussion but no mobility.
* Discomfort response on palpation of surrounding tissue but with no intraoral swelling.
* Patients who stopped medications for the last 12 hours before the procedure
* The radiograph showed only normal or slight widening in the periodontal ligament space of the affected root.
Exclusion Criteria:
* patients with any serious systemic disease
* Patients under the age of eighteen or incapable of giving informed consent
* Patients over forty
* Patients with a mandibular premolar involving multiple canals or huge periapical pathosis
* Patients with severe preoperative pain on biting/mastication or percussion
* Mandibular premolar with open apices
* Mandibular premolar with periodontal involvement
* Retreated cases, sinus tract presence, and swelling of surrounding soft tissues
* patients who had been pregnant and allergic patients with local anesthetic agents
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
40 Years
Study:
NCT06501703
Study Brief:
Protocol Section:
NCT06501703