Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 12:53 PM
Ignite Modification Date:
2025-12-24 @ 12:53 PM
NCT ID:
NCT00280761
Eligibility Criteria:
DISEASE CHARACTERISTICS:
* Must have rectal or sigmoid-rectal junction adenocarcinoma confirmed by sigmoidoscopy and pathologic diagnosis of biopsy sample
* Inferior margin of the tumor less than 15 cm from anal verge by rigid sigmoidoscopy or below the level of S1-2 at surgery
* Candidate for chemotherapy and radiotherapy, as defined by any of the following:
* Tumor staged as T3 or N1-2 by rectal sonography
* Tumor occupying \> 40% of circumference of rectum
* Tumor fixed to extra colonic structures as determined by digital rectal examination
* Tumor \< 5 cm from sphincter mechanism
* Patient has inoperable disease and is being treated for palliation
* Pelvic or anastomotic recurrences of previously resected rectal cancer
* Planning to undergo chemotherapy and radiotherapy
* No sigmoid carcinoma (carcinoma proximal to the pelvic peritoneal reflection)
PATIENT CHARACTERISTICS:
* Not pregnant
PRIOR CONCURRENT THERAPY:
* See Disease Characteristics
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT00280761
Study Brief:
Protocol Section:
NCT00280761