Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 7:06 PM
Ignite Modification Date:
2025-12-24 @ 7:06 PM
NCT ID:
NCT03840057
Eligibility Criteria:
Inclusion Criteria:
* 1\. Adult patients ≥ 18 years of age at the time of presentation;
* 2\. Admitted to Rhode Island Hospital (RIH) emergency room or inpatient services;
* 3\. Presented with hematemesis, coffee ground emesis, or melena;
* 4\. Upper endoscopy is planned within 24 hours of presentation or onset of bleeding.
Exclusion Criteria:
* 1\. Known anaphylactic allergic reaction to erythromycin, azithromycin, and/or metoclopramide;
* 2\. Concurrent use of certain medications associated with tardive dyskinesia (TD):
* a. Fluphenazine,
* b. Haloperidol,
* c. Loxapine,
* d. Paliperidone,
* e. Perphenazine,
* f. Pimozide,
* g. Risperidone,
* h. Thiothixene,
* i. Trifluoperazine;
* 3\. Concurrent use of certain medications associated with torsade de pointes:
* a. Amiodarone,
* b. Chlorpromazine,
* c. Disopyramide,
* d. Dofetilide,
* e. Methadone,
* f. Procainamide,
* g. Quinidine,
* h. Sotalol;
* 4\. Known history of TD, ventricular arrhythmias , or long QT syndrome;
* 5\. Already received erythromycin and/or azithromycin within the past 10 days, or metoclopramide within the past 4 days for other indications;
* 6\. Recipient of hematopoietic stem cell transplant;
* 7\. History of Neisseria gonorrhoeae infection;
* 8\. Pregnancy;
* 9\. Prior gastrectomy.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT03840057
Study Brief:
Protocol Section:
NCT03840057