Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 7:04 PM
Ignite Modification Date:
2025-12-24 @ 7:04 PM
NCT ID:
NCT02872857
Eligibility Criteria:
Inclusion Criteria:
* Spontaneous subarachnoid hemorrhage
* Presentation to hospital within 72 hours of symptoms
* Fisher grade 3 hemorrhage (thick subarachnoid clot) on initial computed tomography (CT) scan
* Hunt and Hess grade 1-5 at time of randomization
* Presence of a cerebral aneurysm on computed tomographic angiography (CTA) or Angiogram for which clipping or coiling is possible
* Ability to obtain medication within 36 hours of presentation
Exclusion Criteria:
* subarachnoid hemorrhage (SAH) due to causes other than aneurysm rupture (trauma, arteriovenous malformation (AVM), mycotic aneurysms, Moyamoya)
* Pre-existing disability with modified Rankin Scale (mRS) score ≥2,
* Renal disease as defined by creatinine clearance less than 9 milliliters/min
* History of severe hepatic impairment (Child-Pugh score of 10-15)
* History of chronic obstructive pulmonary disease (COPD) or asthma
* History of dementia
* Co-morbid conditions likely to complicate therapy, including clinically significant arrhythmia, acquired immune deficiency syndrome (AIDS), autoimmune disease, malignancy, and expected mortality within 72 hours
* Expected mortality within 72 hours as determined by PI, treating neurointensivist and neurosurgeon. (Clinically manifested by no attempt at securing aneurysm)
* Females who are pregnant.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
75 Years
Study:
NCT02872857
Study Brief:
Protocol Section:
NCT02872857