Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 6:58 PM
Ignite Modification Date:
2025-12-24 @ 6:58 PM
NCT ID:
NCT00656357
Eligibility Criteria:
Inclusion Criteria:
* non treatment seeking cocaine dependent
* English speaking
* meet DSM IV TR criteria for cocaine dependence
* pulse 50-90bpm
* systolic BP 85-140 mmHg
* diastolic BP 45-90 mmHg
* essentially normal liver and kidney function blood tests
* ECG normal
* sign informed consent
* negative urine pregnancy test at screening and admission
Exclusion Criteria:
* history or evidence of seizure disorder or brain injury
* previous medically adverse reaction to cocaine, including loss of consciousness, chest pain or epileptic seizure
* neurological disorders, organic brain disease, dementia
* psychiatric disorders such as psychosis, schizophrenia, bipolar disorder, major depression
* history of suicide attempts within past 3 months or suicidal ideation/plan
* history of clinically significant heart disease or hypertension
* family history in 1st degree relatives of early cardiovascular morbidity or mortality
* untreated or unstable medical conditions
* positive HIV test
* pregnant or nursing
* have asthma or are currently using alpha, beta agonists or theophylline or other sympathomimetics
* test positive for other drugs of abuse with the exception of cocaine, cocaine metabolites or marijuana
* any other illness, condition or use of psychotropic medications which preclude safe/successful completion of the study
* currently on parole
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
50 Years
Study:
NCT00656357
Study Brief:
Protocol Section:
NCT00656357