Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 6:56 PM
Ignite Modification Date:
2025-12-24 @ 6:56 PM
NCT ID:
NCT02458157
Eligibility Criteria:
Inclusion Criteria:
* Age ≥ 18 years of age
* Acute Kidney Injury defined according to the KDIGO criteria
* Renal Recovery Score ≤ 60%. (Calculated using www.renal-recovery-score.com)
* Fluid overload defined as a positive fluid balance ≥ 10% of ideal body weight.
* Able to undergo randomization within 12 hours of fulfilling other inclusion criteria
Exclusion Criteria:
* Known pre-hospitalization advanced chronic kidney disease. (eGFR \< 30 mL/minute/1.73 m2 or chronic RRT.)
* Severe hypoxic respiratory failure (use of invasive ventilation and FiO2 \> 80% and PEEP \> 10 cm H2O)
* Severe burn injury (≥ 10% TBSA)
* Severe hypo- or hyper- natremia (\< 120 or \> 155 mmol/l)
* Hepatic coma
* Mentally disabled undergoing forced treatment
* Pregnancy/breast feeding
* Lack of commitment for on-going life support including RRT
* Lack of informed consent
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT02458157
Study Brief:
Protocol Section:
NCT02458157