Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 6:54 PM
Ignite Modification Date:
2025-12-24 @ 6:54 PM
NCT ID:
NCT00473057
Eligibility Criteria:
Inclusion Criteria:
* clinical diagnosis of ischemic stroke lasting for more than 3 hours and less than 90 days from symptoms onset
* neuroimages exams showing ischemic cerebral infarct in the middle cerebral artery territory
* age between 18 and 75 years old
* NIHSS between 4 and 20
* spontaneous re-canalization of the middle cerebral artery documented by TCD or MRI
* signed informed consent
Exclusion Criteria:
* difficult in obtaining vascular access for percutaneous procedures
* vascular impossibility to reach the middle cerebral artery through percutaneous approach
* severe carotid stenosis( \>70%, by Doppler) related to the severe stroke
* neurological worsening (\>4 points in the NIHSS ) due to edema or intracerebral hemorrhage
* primary hematological disease
* neurodegenerative disorder
* previous stroke with mRS \> 2
* intracardiac thrombosis
* auto-imune disorders
* osteopathies that could increase the risk of bone marrow harvesting procedure
* thrombophilias
* liver failure
* chronic renal failure (creatinine \> 2mg/ml)
* life support dependence
* lacunar stroke
* pregnancy
* history of neoplasia or other comorbidity that could impact patient's short-term survival
* any condition that in the judgment of the investigator would place the patient under undue risk
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
75 Years
Study:
NCT00473057
Study Brief:
Protocol Section:
NCT00473057