Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 6:52 PM
Ignite Modification Date:
2025-12-24 @ 6:52 PM
NCT ID:
NCT03022357
Eligibility Criteria:
Inclusion criteria:
* Ability to give informed consent
* Age \> 21 to \< 90 years
* Clinical symptoms suspicious for a diagnosis of Parkinson's disease but clinical uncertainty with regards to a definite diagnosis:
* Clinical symptoms not meeting all of the required UK brain bank diagnostic criteria for the diagnosis of PD
* Clinical features not typically associated with PD and therefore raising the possibility of a different type disorder/movement disorder
* Referred for a DatScan as part of the NHS clinical diagnostic workup to investigate a suspicion for a parkinsonian movement disorder type disease or referred for a research DatScan as part of this study for the diagnostic workup to investigate a suspicion for a parkinsonian movement disorder type disease.
Exclusion criteria:
* Participants with any known contraindication to MRI such as:
* Intracranial aneurysm clips
* Cardiac pacemakers and defibrillators
* Cochlear implants.
* MR-incompatible metal implant or tattoo
* Patients with a significant head tremor
* Claustrophobia
* Pregnant women
* Participants that are felt to be unfit for the MRI scan according to the judgement of medically qualified personnel, either on the research team, or the patient's clinical team. (eg. due to back pain, claustrophobia, acute sickness etc.) This includes patients with signs of impaired temperature regulation such as an extremely high fever.
* (only for those planned for research DatScan) Participants in which a DatScan nuclear medical study can't be performed due to
* Severe allergy to iodide compounds
* Thyroid gland dysfunction
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
21 Years
Maximum Age:
90 Years
Study:
NCT03022357
Study Brief:
Protocol Section:
NCT03022357