Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 6:52 PM
Ignite Modification Date:
2025-12-24 @ 6:52 PM
NCT ID:
NCT04218357
Eligibility Criteria:
Inclusion Criteria:
* Male or female, 21-70 (inclusive) years; women \>7 drinks/week; men \>14 drinks/week;
* meet any DSM-5 criteria score for AUD;
* Breath alcohol Content (BrAC)=0.00 at each visit;
* In good health as confirmed by medical history, physical examination and lab tests;
* Willing to adhere to the study procedures;
* Understand informed consent and questionnaires in English at an 8th grade level
Exclusion Criteria:
* Women who are breastfeeding or have a positive urine screen for pregnancy
* CrCl \< 60mL/min
* Taking aspirin (salicylates may reduce effect of probenecid)
* Taking penicillin
* Taking methotrexate (may increase concentration)
* Taking other medications that may interact with probenecid
* History of suicide attempts in the last three years
* Current diagnosis of another substance disorder(s) other than nicotine, as assessed by self-reports and urine toxicology screen at baseline
* History of hypersensitivity to sulfa drugs
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
21 Years
Maximum Age:
70 Years
Study:
NCT04218357
Study Brief:
Protocol Section:
NCT04218357