Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 6:50 PM
Ignite Modification Date:
2025-12-24 @ 6:50 PM
NCT ID:
NCT01896557
Eligibility Criteria:
Inclusion Criteria:
* Age \> 18 years old
* Coronary artery disease, defined as previous myocardial infarction and/or coronary angioplasty and/or CABG surgery and/or coronariography showing obstruction of at least 50 % in one of major epicardial vessels
* Treatment with Acetylsalicylic Acid (ASA) 100 mg/day
Exclusion Criteria:
* Use on the last 7 days of any other antiplatelet drug beside ASA or oral anticoagulant
* Previous utilization of PPI or ranitidine in the last 7 days before randomization
* Any active bleeding
* Pregnancy or woman of childbearing age without contraceptive method
* Hemoglobin \< 10 g/dL or hematocrit \< 30 %, hematocrit \> 50 %, platelets \< 100.000/mm3 or \> 500.000/mm3; creatinin clearance \< 50 ml/minute
* Percutaneous coronary intervention (PCI) on the last 30 days before randomization (or PCI on the last year when drug-eluted stents are used); CABG surgery on the last 90 days; acute coronary syndrome on the last 60 days
* Active malignant neoplasm
* Active peptic ulcer disease on the last 60 days or upper gastrointestinal bleeding any time in life
* Known allergy to the drugs clopidogrel, ranitidine or omeprazole
* Refuse to participate in the study
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT01896557
Study Brief:
Protocol Section:
NCT01896557