Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 6:48 PM
Ignite Modification Date:
2025-12-24 @ 6:48 PM
NCT ID:
NCT05751057
Eligibility Criteria:
Inclusion Criteria:
* Age \> 18 years old
* Presence of criteria for acute myocardial infarction according to the Fourth Universal Definition of Myocardial Infarction:
* Signs and symptoms of myocardial ischemia
* Detection of acute myocardial injury defined as a rise and/or fall of high-sensitivity cardiac Troponin (hs-cTn) values with at least one value above the 99th percentile Upper Reference Limit at baseline or after presentation.
* Patients scheduled for ICA.
* Written informed consent.
Exclusion Criteria:
* Patients diagnosed with myocardial infarction with ST segment elevation.
* Very High-risk NSTEMI patients according to 2020 ESC Guidelines on Acute Coronary Syndromes:
* Haemodynamic instability
* Cardiogenic shock
* Recurrent/refractory chest pain despite medical treatment
* Life-threatening arrhythmias
* Mechanical complications of MI
* Acute heart failure clearly related to NSTEMI
* ST-segment depression\>1mm/6 leads plus ST-segment elevation aVR and/or V1.
* Legally incompetent to provide informed consent
* Participation in another clinical study.
* Regular known contraindications to CMR at time of inclusion such as:
* Severe renal impairment (eGFR \< 30 ml / min / 1,73 m2) or on dialysis treatment
* Claustrophobia
* Known pregnancy or breast-feeding patients
* Non MR compatible devices
* Known allergy to Gadolinium
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT05751057
Study Brief:
Protocol Section:
NCT05751057