Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 6:43 PM
Ignite Modification Date:
2025-12-24 @ 6:43 PM
NCT ID:
NCT05622357
Eligibility Criteria:
Inclusion Criteria:
* Histopathological proof of rectal adenocarcinoma.
* Tumors located within 15 cm and not less than 4 cm from anal verge.
* Age: ≥ 18 years.
* Locally advanced resectable rectal cancer (cT3/4 N0- Any T N+ve).
* ECOG Performance Status: 0-2.
Exclusion Criteria:
* Non-epithelial rectal malignancy such as sarcoma or lymphoma.
* Unresectable tumors in which surgery will never be possible even if substantial tumor downsizing is seen.
* Recurrent rectal cancer.
* Previous history of malignancy within the last 5 years.
* Previous pelvic irradiation.
* Psychiatric or addictive disorder that would preclude study therapy.
* Concurrent uncontrolled medical conditions.
* Pregnancy or breast feeding.
* Any contraindication to surgery.
* Extensive peripheral neuropathy.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
70 Years
Study:
NCT05622357
Study Brief:
Protocol Section:
NCT05622357